Beclin-1 (Phospho Ser93) rabbit pAb

产品详情

产品名称

Beclin-1 (Phospho Ser93) rabbit pAb

产品货号

YM-A16218

规格

50μL;100μL

种属反应

Human,Rat,Mouse,

实验应用

WB

分子量

60kD

宿主

Rabbit

同种型

IgG

修饰

Phospho

推荐稀释比

WB 1:1000-2000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized phosho peptide around human Beclin-1 (Ser93)

特异性

This antibody detects endogenous levels of Human Beclin-1 (phospho-Ser93)

基因名称

BECN1 GT197

蛋白名称

Beclin-1 (Ser93)

别名

Beclin-1;Coiled-coil myosin-like BCL2-interacting protein;Protein GT197;

基因ID-1

8678

SwissProt

Q14457

背景

beclin 1(BECN1) Homo sapiens This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015],

细胞定位

Cytoplasm . Golgi apparatus, trans-Golgi network membrane ; Peripheral membrane protein . Endosome membrane ; Peripheral membrane protein . Endoplasmic reticulum membrane ; Peripheral membrane protein . Mitochondrion membrane ; Peripheral membrane protein . Endosome . Cytoplasmic vesicle, autophagosome . Interaction with ATG14 promotes translocation to autophagosomes. Expressed in dendrites and cell bodies of cerebellar Purkinje cells (By similarity). .; [Beclin-1-C 35 kDa]: Mitochondrion . Nucleus . Cytoplasm .; [Beclin-1-C 37 kDa]: Mitochondrion .