Desmoplakin (Phospho Ser165/166) rabbit pAb

产品详情

产品名称

Desmoplakin (Phospho Ser165/166) rabbit pAb

产品货号

YM-A16251

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB

分子量

300kD

宿主

Rabbit

同种型

IgG

修饰

Phospho

推荐稀释比

WB 1:1000-2000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized phosho peptide around human Desmoplakin (Ser165 and 166)

特异性

This antibody detects endogenous levels of Human Mouse Rat Desmoplakin (phospho-Ser165 or 166)

基因名称

DSP

蛋白名称

Desmoplakin (Ser165/166)

别名

Desmoplakin;DP;250/210 kDa paraneoplastic pemphigus antigen;

基因ID-1

1832

SwissProt

P15924

背景

This gene encodes a protein that anchors intermediate filaments to desmosomal plaques and forms an obligate component of functional desmosomes. Mutations in this gene are the cause of several cardiomyopathies and keratodermas, including skin fragility-woolly hair syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],

细胞定位

Cell junction, desmosome . Cytoplasm, cytoskeleton . Cell membrane . Innermost portion of the desmosomal plaque. Colocalizes with epidermal KRT5-KRT14 and simple KRT8-KRT18 keratins and VIM intermediate filaments network (PubMed:12802069). Localizes at the intercalated disk in cardiomyocytes (By similarity). .