DR6 (Phospho Ser562) rabbit pAb

产品详情

产品名称

DR6 (Phospho Ser562) rabbit pAb

产品货号

YM-A16254

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB

分子量

72kD

宿主

Rabbit

同种型

IgG

修饰

Phospho

推荐稀释比

WB 1:1000-2000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized phosho peptide around human DR6 (Ser562)

特异性

This antibody detects endogenous levels of Human Mouse Rat DR6 (phospho-Ser562)

基因名称

TNFRSF21 DR6 UNQ437/PRO868

蛋白名称

DR6 (Ser562)

别名

Tumor necrosis factor receptor superfamily member 21;Death receptor 6;CD antigen CD358;

基因ID-1

27242

SwissProt

O75509

背景

This gene encodes a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal kinase 1), and induces cell apoptosis. Through its death domain, the encoded receptor interacts with tumor necrosis factor receptor type 1-associated death domain (TRADD) protein, which is known to mediate signal transduction of tumor necrosis factor receptors. Knockout studies in mice suggest that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation. [provided by RefSeq, Jul 2013],

细胞定位

Cell membrane ; Single-pass type I membrane protein .