eIF4G (Phospho Ser1108) rabbit pAb

产品详情

产品名称

eIF4G (Phospho Ser1108) rabbit pAb

产品货号

YM-A16265

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB

分子量

180kD

宿主

Rabbit

同种型

IgG

修饰

Phospho

推荐稀释比

WB 1:1000-2000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized phosho peptide around human eIF4G (Ser1108)

特异性

This antibody detects endogenous levels of Human Mouse Rat eIF4G (phospho-Ser1108)

基因名称

EIF4G1 EIF4F EIF4G EIF4GI

蛋白名称

eIF4G (Ser1108)

别名

Eukaryotic translation initiation factor 4 gamma 1;eIF-4-gamma 1;eIF-4G 1;eIF-4G1;p220;

基因ID-1

1981

SwissProt

Q04637

背景

The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. [provided by RefSeq, Aug 2010],

细胞定位

Cytoplasm, Stress granule .