IGF-I Receptor β (Phospho Tyr1131) rabbit pAb

产品详情

产品名称

IGF-I Receptor β (Phospho Tyr1131) rabbit pAb

产品货号

YM-A16292

规格

50μL;100μL

种属反应

Human,Rat,Mouse,

实验应用

WB

分子量

pro:155kD,recetor beta:95kD

宿主

Rabbit

同种型

IgG

修饰

Phospho

推荐稀释比

WB 1:1000-2000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized phosho peptide around human IGF-I Receptor β (Tyr1131)

特异性

This antibody detects endogenous levels of Human IGF-I Receptor β (phospho-Tyr1131)

基因名称

IGF1R

蛋白名称

IGF-I Receptor β (Tyr1131)

别名

Insulin-like growth factor 1 receptor;Insulin-like growth factor I receptor;IGF-I receptor;CD antigen CD221;[Cleaved into: Insulin-like growth factor 1 receptor alpha chain;Insulin-like growth factor 1 receptor beta chain]

基因ID-1

3480

SwissProt

P08069

背景

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014],

细胞定位

Cell membrane ; Single-pass type I membrane protein .