IκB-α (Phospho Ser32) rabbit pAb

产品详情

产品名称

IκB-α (Phospho Ser32) rabbit pAb

产品货号

YM-A16305

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,IHC

分子量

40kD

宿主

Rabbit

同种型

IgG

修饰

Phospho

推荐稀释比

WB 1:500-2000;IHC 1:50-300

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized phosho peptide around human IκBα (Ser32)

特异性

This antibody detects endogenous levels of Human Mouse Rat IκBα (phospho-Ser32)

基因名称

NFKBIA IKBA MAD3 NFKBI

蛋白名称

NF-kappa-B inhibitor alpha

别名

NF-kappa-B inhibitor alpha;I-kappa-B-alpha;IkB-alpha;IkappaBalpha;Major histocompatibility complex enhancer-binding protein MAD3;

基因ID-1

4792

SwissProt

P25963

背景

This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011],

细胞定位

Cytoplasm. Nucleus. Shuttles between the nucleus and the cytoplasm by a nuclear localization signal (NLS) and a CRM1-dependent nuclear export. .