MKK7 (Phospho Ser271/Thr275) rabbit pAb

产品详情

产品名称

MKK7 (Phospho Ser271/Thr275) rabbit pAb

产品货号

YM-A16335

规格

50μL;100μL

种属反应

Human,Rat,Mouse,

实验应用

WB,ELISA,IHC

分子量

47kD

宿主

Rabbit

同种型

IgG

修饰

Phospho

推荐稀释比

WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized phosho peptide around human MKK7 (Ser271 and Thr275)

特异性

This antibody detects endogenous levels of Human MKK7 (phospho-Ser271 or Thr275)

基因名称

MAP2K7 JNKK2 MEK7 MKK7 PRKMK7 SKK4

蛋白名称

MKK7 (Ser271/Thr275)

别名

Dual specificity mitogen-activated protein kinase kinase 7;MAP kinase kinase 7;MAPKK 7;JNK-activating kinase 2;MAPK/ERK kinase 7;MEK 7;Stress-activated protein kinase kinase 4;SAPK kinase 4;SAPKK-4;SAPKK4;c-Jun N-terminal kinase kinase 2;JNK kinase 2;JNKK 2;

基因ID-1

5609

SwissProt

O14733

背景

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],

细胞定位

Nucleus. Cytoplasm .