Numb (Phospho Ser276) rabbit pAb

产品详情

产品名称

Numb (Phospho Ser276) rabbit pAb

产品货号

YM-A16352

规格

50μL;100μL

种属反应

Human,Rat,Mouse,

实验应用

WB

分子量

70kD

宿主

Rabbit

同种型

IgG

修饰

Phospho

推荐稀释比

WB 1:1000-2000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized phosho peptide around human Numb (Ser276)

特异性

This antibody detects endogenous levels of Human Numb (phospho-Ser276)

基因名称

NUMB

蛋白名称

Numb (Ser276)

别名

Protein numb homolog;h-Numb;Protein S171;

基因ID-1

8650

SwissProt

P49757

背景

The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016],

细胞定位

Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Endosome membrane ; Peripheral membrane protein ; Cytoplasmic side . Localizes to perinuclear endosomes in an AAK1-dependent manner. .