RIP3 (Phospho Ser227) rabbit pAb

产品详情

产品名称

RIP3 (Phospho Ser227) rabbit pAb

产品货号

YM-A16388

规格

50μL;100μL

种属反应

Human

实验应用

WB,ELISA,IHC

分子量

56-70kD

宿主

Rabbit

同种型

IgG

修饰

Phospho

推荐稀释比

WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized phosho peptide around human RIP3 (Ser227)

特异性

This antibody detects endogenous levels of Human RIP3 (phospho-Ser227)

基因名称

RIPK3 RIP3

蛋白名称

RIP3 (Ser227)

别名

Receptor-interacting serine/threonine-protein kinase 3;RIP-like protein kinase 3;Receptor-interacting protein 3;RIP-3;

基因ID-1

11035

SwissProt

Q9Y572

背景

The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. [provided by RefSeq, Jul 2008],

细胞定位

Cytoplasm, cytosol . Nucleus . Mainly cytoplasmic. Present in the nucleus in response to influenza A virus (IAV) infection. .