SF3B1 (Phospho Thr313) rabbit pAb

产品详情

产品名称

SF3B1 (Phospho Thr313) rabbit pAb

产品货号

YM-A16404

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,IHC

分子量

145kD

宿主

Rabbit

同种型

IgG

修饰

Phospho

推荐稀释比

WB 1:500-2000;IHC 1:50-300

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized phosho peptide around human SF3B1 (Thr313)

特异性

This antibody detects endogenous levels of Human Mouse SF3B1 (phospho-Thr313)

基因名称

SF3B1 SAP155

蛋白名称

SF3B1 (Thr313)

别名

Splicing factor 3B subunit 1;Pre-mRNA-splicing factor SF3b 155 kDa subunit;SF3b155;Spliceosome-associated protein 155;SAP 155;

基因ID-1

23451

SwissProt

O75533

背景

This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

细胞定位

Nucleus . Nucleus speckle. During mitosis, transiently dispersed from the nuclear speckles to the cytoplasm.