TBK1/NAK (Phospho Ser172) rabbit pAb

产品详情

产品名称

TBK1/NAK (Phospho Ser172) rabbit pAb

产品货号

YM-A16440

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

ELISA

分子量

80kD

宿主

Rabbit

同种型

IgG

修饰

Phospho

推荐稀释比

ELISA 1:5000-20000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized phosho peptide around human TBK1 and NAK (Ser172)

特异性

This antibody detects endogenous levels of Human Mouse TBK1/NAK (phospho-Ser172)

基因名称

TBK1 NAK

蛋白名称

TBK1/NAK (Ser172)

别名

Serine/threonine-protein kinase TBK1;NF-kappa-B-activating kinase;T2K;TANK-binding kinase 1;

基因ID-1

29110

SwissProt

Q9UHD2

背景

The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. [provided by RefSeq, Oct 2010],

细胞定位

Cytoplasm . Upon mitogen stimulation or triggering of the immune system, TBK1 is recruited to the exocyst by EXOC2. .