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产品详情
产品名称
BLK (Phospho Tyr389) rabbit pAb
产品货号
YM-A16581
规格
50μL;100μL
种属反应
Human,Mouse,Rat
实验应用
WB
分子量
宿主
Rabbit
同种型
IgG
修饰
Phospho
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克降性
Polyclonal
克隆号
免疫原
Synthesized peptide derived from human BLK (Phospho-Tyr389)
特异性
This antibody detects endogenous levels of BLK (Phospho-Tyr389) at Human, Mouse,Rat
基因名称
BLK
蛋白名称
BLK (Phospho-Tyr389)
别名
Tyrosine-protein kinase Blk;B lymphocyte kinase;p55-Blk;
基因ID-1
640
SwissProt
P51451
背景
This gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors. [provided by RefSeq, Aug 2010],
细胞定位
Cell membrane ; Lipid-anchor . Present and active in lipid rafts. Membrane location is required for the phosphorylation of CD79A and CD79B (By similarity). .
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