TGFBR2 (Phospho Tyr284) rabbit pAb

产品详情

产品名称

TGFBR2 (Phospho Tyr284) rabbit pAb

产品货号

YM-A16584

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB

分子量

75kD

宿主

Rabbit

同种型

IgG

修饰

Phospho

推荐稀释比

WB 1:500-2000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human TGFBR2 (Phospho-Tyr284)

特异性

This antibody detects endogenous levels of TGFBR2 (Phospho-Tyr284) at Human, Mouse,Rat

基因名称

TGFBR2

蛋白名称

TGFBR2 (Phospho-Tyr284)

别名

TGF-beta receptor type-2;TGFR-2;TGF-beta type II receptor;Transforming growth factor-beta receptor type II;TGF-beta receptor type II;TbetaR-II;

基因ID-1

7048

SwissProt

P37173

背景

This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008],

细胞定位

Cell membrane ; Single-pass type I membrane protein . Membrane raft .; [Isoform 3]: Secreted .