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产品详情
产品名称
ILK-1 (Phospho Ser343) rabbit pAb
产品货号
YM-A16588
规格
50μL;100μL
种属反应
Human,Mouse,Rat
实验应用
WB
分子量
宿主
Rabbit
同种型
IgG
修饰
Phospho
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克降性
Polyclonal
克隆号
免疫原
Synthesized peptide derived from human ILK-1 (Phospho-Ser343)
特异性
This antibody detects endogenous levels of ILK-1 (Phospho-Ser343) at Human, Mouse,Rat
基因名称
ILK ILK1 ILK2
蛋白名称
ILK-1 (Phospho-Ser343)
别名
Integrin-linked protein kinase;59 kDa serine/threonine-protein kinase;ILK-1;ILK-2;p59ILK;
基因ID-1
3611
SwissProt
Q13418
背景
This gene encodes a protein with a kinase-like domain and four ankyrin-like repeats. The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins, where it regulates integrin-mediated signal transduction. Activity of this protein is important in the epithelial to mesenchymal transition, and over-expression of this gene is implicated in tumor growth and metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013],
细胞定位
Cell junction, focal adhesion . Cell membrane; Peripheral membrane protein; Cytoplasmic side . Cell projection, lamellipodium . Cytoplasm, myofibril, sarcomere .
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