SRPK1 (Phospho Thr601) rabbit pAb

产品详情

产品名称

SRPK1 (Phospho Thr601) rabbit pAb

产品货号

YM-A16604

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB

分子量

74kD

宿主

Rabbit

同种型

IgG

修饰

Phospho

推荐稀释比

WB 1:500-2000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human SRPK1 (Phospho-Thr601)

特异性

This antibody detects endogenous levels of SRPK1 (Phospho-Thr601) at Human, Mouse,Rat

基因名称

SRPK1

蛋白名称

SRPK1 (Phospho-Thr601)

别名

SRSF protein kinase 1;SFRS protein kinase 1;Serine/arginine-rich protein-specific kinase 1;SR-protein-specific kinase 1;

基因ID-1

6732

SwissProt

Q96SB4

背景

This gene encodes a serine/arginine protein kinase specific for the SR (serine/arginine-rich domain) family of splicing factors. The protein localizes to the nucleus and the cytoplasm. It is thought to play a role in regulation of both constitutive and alternative splicing by regulating intracellular localization of splicing factors. Alternative splicing of this gene results in multiple transcript variants. Additional alternatively spliced transcript variants have been described for this gene, but their full length nature have not been determined.[provided by RefSeq, Jul 2010],

细胞定位

[Isoform 2]: Cytoplasm. Nucleus. Nucleus matrix. Microsome. Shuttles between the nucleus and the cytoplasm. Inhibition of the Hsp90 ATPase activity, osmotic stress and interaction with HHV-1 ICP27 protein can induce its translocation to the nucleus. KAT5/TIP60 inhibits its nuclear translocation.; [Isoform 1]: Cytoplasm. Nucleus matrix. Microsome. Mainly localized in the microsomal fraction and the cytoplasm, and to a lesser extent in the nuclear matrix.; Cytoplasm . Nucleus, nucleoplasm . Nucleus speckle . Chromosome . Preferentially localizes to the promoter of gene coding regions. .