EIF6 (Phospho Ser235) rabbit pAb

产品详情

产品名称

EIF6 (Phospho Ser235) rabbit pAb

产品货号

YM-A16612

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB

分子量

宿主

Rabbit

同种型

IgG

修饰

Phospho

推荐稀释比

WB 1:500-2000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human EIF6 (Phospho-Ser235)

特异性

This antibody detects endogenous levels of EIF6 (Phospho-Ser235) at Human, Mouse,Rat

基因名称

EIF6 EIF3A ITGB4BP OK/SW-cl.27

蛋白名称

EIF6 (Phospho-Ser235)

别名

Eukaryotic translation initiation factor 6;eIF-6;B;2;GCN homolog;B4 integrin interactor;CAB;p27;BBP;

基因ID-1

3692

SwissProt

P56537

背景

Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple non-protein coding transcript variants and variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2012],

细胞定位

Cytoplasm. Nucleus, nucleolus. Shuttles between cytoplasm and nucleus/nucleolus.