HP1-β (Phospho Thr51) rabbit pAb

产品详情

产品名称

HP1-β (Phospho Thr51) rabbit pAb

产品货号

YM-A16642

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB

分子量

宿主

Rabbit

同种型

IgG

修饰

Phospho

推荐稀释比

WB 1:500-2000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human HP1-β (Phospho-Thr51)

特异性

This antibody detects endogenous levels of HP1-β (Phospho-Thr51) at Human, Mouse,Rat

基因名称

CBX1 CBX

蛋白名称

HP1-β (Phospho-Thr51)

别名

Chromobox protein homolog 1;HP1Hsbeta;Heterochromatin protein 1 homolog beta;HP1 beta;Heterochromatin protein p25;M31;Modifier 1 protein;p25beta;

基因ID-1

10951

SwissProt

P83916

背景

This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008],

细胞定位

Nucleus . Unassociated with chromosomes during mitosis.