STAT4 (Phospho Ser721) Rabbit pAb

产品详情

产品名称

STAT4 (Phospho Ser721) Rabbit pAb

产品货号

YM-A16739

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

IHC,WB

分子量

86kD

宿主

Rabbit

同种型

修饰

Phospho

推荐稀释比

WB 1:500-2000;IHC 1:50-200

组成

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human STAT4 (Phospho Ser721)

特异性

This antibody detects endogenous levels of STAT4 (Phospho Ser721) Rabbit pAb at Human, Mouse

基因名称

STAT4

蛋白名称

Signal transducer and activator of transcription 4

别名

Signal transducer and activator of transcription 4

基因ID-1

6775

SwissProt

Q14765

背景

signal transducer and activator of transcription 4(STAT4) Homo sapiens The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011],

细胞定位

Cytoplasm. Nucleus. Translocated into the nucleus in response to phosphorylation.