eIF2α (Phospho Ser51) (PTR1316) mouse mAb

产品详情

产品名称

eIF2α (Phospho Ser51) (PTR1316) mouse mAb

产品货号

YM-A16759

规格

50μL;100μL

种属反应

Human,Mouse,Rat,

实验应用

WB,IF,ELISA

分子量

40kD,90kD

宿主

Mouse

同种型

IgG2b,Kappa

修饰

Phospho

推荐稀释比

WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

Protein G

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Monoclonal

克隆号

PTR1316

免疫原

Synthesized peptide derived from human eIF2α AA range: 1-100

特异性

This antibody detects endogenous levels of eIF2α (Phospho Ser51) protein.

基因名称

EIF2S1 EIF2A

蛋白名称

Eukaryotic translation initiation factor 2 subunit 1 (Eukaryotic translation initiation factor 2 subunit alpha) (eIF-2-alpha) (eIF-2A) (eIF-2alpha)

别名

基因ID-1

1965

SwissProt

P05198

背景

eukaryotic translation initiation factor 2 subunit alpha(EIF2S1) Homo sapiens The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010],

细胞定位