ABHD12 Polyclonal Antibody

产品详情

产品名称

ABHD12 Polyclonal Antibody

产品货号

YM-A16818

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,IHC,IF,ELISA

分子量

45kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human ABHD12. AA range:231-280

特异性

ABHD12 Polyclonal Antibody detects endogenous levels of ABHD12 protein.

基因名称

ABHD12

蛋白名称

Monoacylglycerol lipase ABHD12

别名

ABHD12;C20orf22;Monoacylglycerol lipase ABHD12;2-arachidonoylglycerol hydrolase;Abhydrolase domain-containing protein 12

基因ID-1

26090

SwissProt

Q8N2K0

背景

This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG), the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract), resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jan 2011],

细胞定位

Endoplasmic reticulum membrane ; Single-pass membrane protein .