ABHD7 Polyclonal Antibody

产品详情

产品名称

ABHD7 Polyclonal Antibody

产品货号

YM-A16825

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,ELISA

分子量

42kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human ABHD7. AA range:101-150

特异性

ABHD7 Polyclonal Antibody detects endogenous levels of ABHD7 protein.

基因名称

EPHX4

蛋白名称

Epoxide hydrolase 4

别名

EPHX4;ABHD7;EPHXRP;Epoxide hydrolase 4;Abhydrolase domain-containing protein 7;Epoxide hydrolase-related protein

基因ID-1

253152

SwissProt

Q8IUS5

背景

The α/β hydrolase superfamily comprise diverse members that are involved in important biochemical processes and related to various diseases. They have unrelated sequences, various substrates, and different kinds of catalytic activities, yet they share the same canonical α/β hydrolase fold, which consists of an eight-stranded parallel α/β structure. They are also characterized by a catalytic triad composed of a histidine, an acid and a nucleophile. Members of this superfamily are often drug targets for treating diseases, such as diabetes, Alzheimer's disease, obesity and blood clotting disorders. The Ab hydrolase domain containing (ABHD) gene subfamily is comprised of 15 mostly uncharacterized members, most of which utilize a serine nucleophile to form the G-X-S-X-G nucleophile elbow. ABHD7 is a 362 amino acid single-pass type II membrane protein that belongs to the AB hydrolase superfamily and the Epoxide hydrolase family.

细胞定位

Membrane ; Single-pass type II membrane protein .