ACCα Polyclonal Antibody

产品详情

产品名称

ACCα Polyclonal Antibody

产品货号

YM-A16836

规格

50μL;100μL

种属反应

Human,Mouse,Rat,Bovine,Canine

实验应用

WB,IHC,IF,ELISA

分子量

265kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human Acetyl-CoA Carboxylase. AA range:46-95

特异性

ACCα Polyclonal Antibody detects endogenous levels of ACCα protein.

基因名称

ACACA

蛋白名称

Acetyl-CoA carboxylase 1

别名

ACACA;ACAC;ACC1;ACCA;Acetyl-CoA carboxylase 1;ACC1;ACC-alpha

基因ID-1

31

SwissProt

Q13085

背景

Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

细胞定位

Cytoplasm, cytosol .