Adducin α/β Polyclonal Antibody

产品详情

产品名称

Adducin α/β Polyclonal Antibody

产品货号

YM-A16887

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,IHC,IP,IF,ELISA

分子量

80kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;IP 2-5 ug:mg lysate;IF 1:200-1:1000;ELISA 1:40000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human ADD1. AA range:688-737

特异性

Adducin α/β Polyclonal Antibody detects endogenous levels of Adducin α/β protein.

基因名称

ADD1/ADD2

蛋白名称

Alpha-adducin/Beta-adducin

别名

ADD1;ADDA;Alpha-adducin;Erythrocyte adducin subunit alpha;ADD2;ADDB;Beta-adducin;Erythrocyte adducin subunit beta

基因ID-1

118;119

SwissProt

P35611;P35612

背景

adducin 1(ADD1) Homo sapiens Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described. [provided by RefSeq, Jul 2008],

细胞定位

Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side.