ALY Polyclonal Antibody

产品详情

产品名称

ALY Polyclonal Antibody

产品货号

YM-A16952

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,ELISA

分子量

27kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human THOC4. AA range:121-170

特异性

ALY Polyclonal Antibody detects endogenous levels of ALY protein.

基因名称

ALYREF

蛋白名称

THO complex subunit 4

别名

ALYREF;ALY;BEF;THOC4;THO complex subunit 4;Tho4;Ally of AML-1 and LEF-1;Aly/REF export factor;Transcriptional coactivator Aly/REF;bZIP-enhancing factor BEF

基因ID-1

10189

SwissProt

Q86V81

背景

The protein encoded by this gene is a heat stable, nuclear protein and functions as a molecular chaperone. It is thought to regulate dimerization, DNA binding, and transcriptional activity of basic region-leucine zipper (bZIP) proteins. [provided by RefSeq, Jul 2008],

细胞定位

Nucleus . Nucleus speckle . Cytoplasm . Colocalizes with the core EJC, ALYREF/THOC4, NXF1 and DDX39B in the nucleus and nuclear speckles. Travels to the cytoplasm as part of the exon junction complex (EJC) bound to mRNA (PubMed:19324961). Localizes to regions surrounding nuclear speckles known as perispeckles in which TREX complex assembly seems to occur (PubMed:23826332). .