A-Myb Polyclonal Antibody

产品详情

产品名称

A-Myb Polyclonal Antibody

产品货号

YM-A16968

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,ELISA

分子量

85kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human MYB-A. AA range:231-280

特异性

A-Myb Polyclonal Antibody detects endogenous levels of A-Myb protein.

基因名称

MYBL1

蛋白名称

Myb-related protein A

别名

MYBL1;AMYB;Myb-related protein A;A-Myb;Myb-like protein 1

基因ID-1

4603

SwissProt

P10243

背景

function:Strong transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Could have a role in the proliferation and/or differentiation of neurogenic, spermatogenic and B-lymphoid cells.,similarity:Contains 3 HTH myb-type DNA-binding domains.,subunit:Component of the DREAM complex (also named LINC complex) at least composed of E2F4, E2F5, LIN9, LIN37, LIN52, LIN54, MYBL1, MYBL2, RBL1, RBL2, RBBP4, TFDP1 and TFDP2. The complex exists in quiescent cells where it represses cell cycle-dependent genes. It dissociates in S phase when LIN9, LIN37, LIN52 and LIN54 form a subcomplex that binds to MYBL2.,tissue specificity:Expressed in a variety of lymphoid and solid tumor lines cultured in vitro.,

细胞定位

Nucleus .