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产品详情
产品名称
ANT4 Polyclonal Antibody
产品货号
YM-A16984
规格
50μL;100μL
种属反应
Human,Mouse
实验应用
WB,IHC,IF,ELISA
分子量
35kD
宿主
Rabbit
同种型
IgG
修饰
Unmodified
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克降性
Polyclonal
克隆号
免疫原
The antiserum was produced against synthesized peptide derived from human SLC25A31. AA range:131-180
特异性
ANT4 Polyclonal Antibody detects endogenous levels of ANT4 protein.
基因名称
SLC25A31
蛋白名称
ADP/ATP translocase 4
别名
SLC25A31;AAC4;ANT4;SFEC;ADP/ATP translocase 4;ADP;ATP carrier protein 4;Adenine nucleotide translocator 4;ANT 4;Solute carrier family 25 member 31;Sperm flagellar energy carrier protein
基因ID-1
83447
SwissProt
Q9H0C2
背景
The protein encoded by this gene is a member of the ADP/ATP carrier family of proteins that exchange cytosolic ADP for matrix ATP in the mitochondria. Cells over-expressing this gene have been shown to display an anti-apoptotic phenotype. This protein is also thought to play a role in spermatogenesis, where it is believed to associate with a part of the flagellar cytoskeleton and with glycolytic enzymes. Male mice with mutations in the mouse ortholog of this gene are sterile and spermatocytes display an early meiotic arrest phenotype. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016],
细胞定位
Mitochondrion inner membrane ; Multi-pass membrane protein . Membrane ; Multi-pass membrane protein . Cell projection, cilium, flagellum membrane ; Multi-pass membrane protein . In sperm flagellum this protein is located in the fibrous sheath, a non-mitochondrial region (PubMed:17137571). May localize to non-mitochondrial membranes (PubMed:27641616). .
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