APOBEC3A Polyclonal Antibody

产品详情

产品名称

APOBEC3A Polyclonal Antibody

产品货号

YM-A17002

规格

50μL;100μL

种属反应

Human

实验应用

WB,ELISA

分子量

26kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human APOBEC3A. AA range:27-76

特异性

APOBEC3A Polyclonal Antibody detects endogenous levels of APOBEC3A protein.

基因名称

APOBEC3A

蛋白名称

Probable DNA dC->dU-editing enzyme APOBEC-3A

别名

APOBEC3A;Probable DNA dC->dU-editing enzyme APOBEC-3A;Phorbolin-1

基因ID-1

200315

SwissProt

P31941

背景

This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein encoded by this gene lacks the zinc binding activity of other family members. The protein plays a role in immunity, by restricting transmission of foreign DNA such as viruses. One mechanism of foreign DNA restriction is deamination of foreign double-stranded DNA cytidines to uridines, which leads to DNA degradation. However, other mechanisms are also thought to be involved, as anti-viral effect is not dependent on deaminase activity. Two transcript variants encoding different isoforms have been found for this gene. [provided b

细胞定位

Nucleus. Cytoplasm.