AR α2A Polyclonal Antibody

产品详情

产品名称

AR α2A Polyclonal Antibody

产品货号

YM-A17027

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,IHC,IF,ELISA

分子量

48kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human Adrenergic Receptor alpha-2A. AA range:331-380

特异性

AR α2A Polyclonal Antibody detects endogenous levels of AR α2A protein.

基因名称

ADRA2A

蛋白名称

Alpha-2A adrenergic receptor

别名

ADRA2A;ADRA2R;ADRAR;Alpha-2A adrenergic receptor;Alpha-2 adrenergic receptor subtype C10;Alpha-2A adrenoreceptor;Alpha-2A adrenoceptor;Alpha-2AAR

基因ID-1

150

SwissProt

P08913

背景

Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons; the alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes alpha2A subtype and it contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008],

细胞定位

Cell membrane ; Multi-pass membrane protein .