Arginase I Polyclonal Antibody

产品详情

产品名称

Arginase I Polyclonal Antibody

产品货号

YM-A17040

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,IHC,IF,ELISA

分子量

35kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

IHC: 100-300;WB 1:500-1:2000;ELISA 1:5000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human ARG1. AA range:61-110

特异性

Arginase I Polyclonal Antibody detects endogenous levels of Arginase I protein.

基因名称

ARG1

蛋白名称

Arginase-1

别名

ARG1;Arginase-1;Liver-type arginase;Type I arginase

基因ID-1

383

SwissProt

P05089

背景

Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],

细胞定位

Cytoplasm . Cytoplasmic granule . Localized in azurophil granules of neutrophils (PubMed:15546957). .