ARHGAP22 Polyclonal Antibody

产品详情

产品名称

ARHGAP22 Polyclonal Antibody

产品货号

YM-A17047

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,IHC,IF,ELISA

分子量

77kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human RHG22. AA range:565-614

特异性

ARHGAP22 Polyclonal Antibody detects endogenous levels of ARHGAP22 protein.

基因名称

ARHGAP22

蛋白名称

Rho GTPase-activating protein 22

别名

ARHGAP22;RHOGAP2;Rho GTPase-activating protein 22;Rho-type GTPase-activating protein 22

基因ID-1

58504

SwissProt

Q7Z5H3

背景

This gene encodes a member of the GTPase activating protein family which activates a GTPase belonging to the RAS superfamily of small GTP-binding proteins. The encoded protein is insulin-responsive, is dependent on the kinase Akt and requires the Akt-dependent 14-3-3 binding protein which binds sequentially to two serine residues. The result of these interactions is regulation of cell motility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011],

细胞定位

Cytoplasm . Nucleus . Mainly cytoplasmic. Some fraction is nuclear (By similarity). .