Ataxin-2L Polyclonal Antibody

产品详情

产品名称

Ataxin-2L Polyclonal Antibody

产品货号

YM-A17100

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,ELISA

分子量

113kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human ATXN2L. AA range:571-620

特异性

Ataxin-2L Polyclonal Antibody detects endogenous levels of Ataxin-2L protein.

基因名称

ATXN2L

蛋白名称

Ataxin-2-like protein

别名

ATXN2L;A2D;A2LG;A2LP;A2RP;Ataxin-2-like protein;Ataxin-2 domain protein;Ataxin-2-related protein

基因ID-1

11273

SwissProt

Q8WWM7

背景

This gene encodes an ataxin type 2 related protein of unknown function. This protein is a member of the spinocerebellar ataxia (SCAs) family, which is associated with a complex group of neurodegenerative disorders. Several alternatively spliced transcripts encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

细胞定位

Membrane ; Peripheral membrane protein . Cytoplasm . Nucleus speckle . Cytoplasmic granule . Predominantly cytoplasmic but is also detected in nuclear speckles (PubMed:23209657). Component of cytoplasmic stress granules (PubMed:23209657). Inhibition of methylation alters nuclear localization (PubMed:25748791). Methylation does not seem to be required for localization to stress granules under stress conditions (PubMed:25748791). .