ATPBD3 Polyclonal Antibody

产品详情

产品名称

ATPBD3 Polyclonal Antibody

产品货号

YM-A17139

规格

50μL;100μL

种属反应

Human,Rat,Mouse,

实验应用

WB,ELISA

分子量

36kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human ATPBD3. AA range:291-340

特异性

ATPBD3 Polyclonal Antibody detects endogenous levels of ATPBD3 protein.

基因名称

CTU1

蛋白名称

Cytoplasmic tRNA 2-thiolation protein 1

别名

CTU1;ATPBD3;NCS6;Cytoplasmic tRNA 2-thiolation protein 1;ATP-binding domain-containing protein 3;Cancer-associated gene protein;Cytoplasmic tRNA adenylyltransferase 1

基因ID-1

90353

SwissProt

Q7Z7A3

背景

function:Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.,pathway:tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.,similarity:Belongs to the ttcA family. CTU1/NCS6/ATPBD3 subfamily.,subunit:Component of a complex at least composed of URM1, CTU2/NCS2 and ATPBD3/NCS6. May for a heterodimer with CTU2/NCS2.,

细胞定位

Cytoplasm.