Bradykinin B1 R Polyclonal Antibody

产品详情

产品名称

Bradykinin B1 R Polyclonal Antibody

产品货号

YM-A17224

规格

50μL;100μL

种属反应

Human,Rat,Mouse,

实验应用

WB,IF,ELISA

分子量

40kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human BDKRB1. AA range:201-250

特异性

Bradykinin B1 R Polyclonal Antibody detects endogenous levels of Bradykinin B1 R protein.

基因名称

BDKRB1

蛋白名称

B1 bradykinin receptor

别名

BDKRB1;BRADYB1;B1 bradykinin receptor;B1R;BK-1 receptor

基因ID-1

623

SwissProt

P46663

背景

Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],

细胞定位

Cell membrane; Multi-pass membrane protein.