CaMKIIβ/γ/δ Polyclonal Antibody

产品详情

产品名称

CaMKIIβ/γ/δ Polyclonal Antibody

产品货号

YM-A17324

规格

50μL;100μL

种属反应

Human,Mouse,Rat,Pig

实验应用

WB,IHC,IF,ELISA

分子量

50kD,65kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human CaMK2-beta/gamma/delta. AA range:253-302

特异性

CaMKIIβ/γ/δ Polyclonal Antibody detects endogenous levels of CaMKIIβ/γ/δ protein.

基因名称

CAMK2B

蛋白名称

Calcium/calmodulin-dependent protein kinase type II subunit beta

别名

CAMK2B;CAM2;CAMK2;CAMKB;Calcium/calmodulin-dependent protein kinase type II subunit beta;CaM kinase II subunit beta;CaMK-II subunit beta;CAMK2G;CAMK;CAMK-II;CAMKG;Calcium/calmodulin-dependent protein kinase type II subunit gamma;

基因ID-1

816;817;818

SwissProt

Q13554;Q13555;Q13557

背景

The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014],

细胞定位

Cytoplasm, cytoskeleton . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Sarcoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell junction, synapse . In slow-twitch muscle, evenly distributed between longitudinal SR and junctional SR.