CD158f2 Polyclonal Antibody

产品详情

产品名称

CD158f2 Polyclonal Antibody

产品货号

YM-A17403

规格

50μL;100μL

种属反应

Human

实验应用

WB,IF,ELISA

分子量

40kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human KIR2DL5B. AA range:161-210

特异性

CD158f2 Polyclonal Antibody detects endogenous levels of CD158f2 protein.

基因名称

KIR2DL5B

蛋白名称

Killer cell immunoglobulin-like receptor 2DL5B

别名

KIR2DL5B;CD158F;CD158F2;KIR2DL5;KIR2DLX;Killer cell immunoglobulin-like receptor 2DL5B;CD158 antigen-like family member F2;Killer cell immunoglobulin-like receptor 2DLX;CD antigen CD158f2

基因ID-1

553128

SwissProt

Q8NHK3

背景

killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 5B(KIR2DL5B) Homo sapiens Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the

细胞定位

Cell membrane; Single-pass type I membrane protein.