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产品详情
产品名称
Chfr Polyclonal Antibody
产品货号
YM-A17542
规格
50μL;100μL
种属反应
Human,Mouse,Rat
实验应用
WB,ELISA
分子量
75kD
宿主
Rabbit
同种型
IgG
修饰
Unmodified
推荐稀释比
WB 1:500-1:2000;ELISA 1:5000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克降性
Polyclonal
克隆号
免疫原
Synthesized peptide derived from the Internal region of human Chfr.
特异性
Chfr Polyclonal Antibody detects endogenous levels of Chfr protein.
基因名称
CHFR
蛋白名称
E3 ubiquitin-protein ligase CHFR
别名
CHFR;RNF196;E3 ubiquitin-protein ligase CHFR;Checkpoint with forkhead and RING finger domains protein;RING finger protein 196
基因ID-1
55743
SwissProt
Q96EP1
背景
This gene encodes an E3 ubiquitin-protein ligase required for the maintenance of the antephase checkpoint that regulates cell cycle entry into mitosis and, therefore, may play a key role in cell cycle progression and tumorigenesis. The encoded protein has an N-terminal forkhead-associated domain, a central RING-finger domain, and a cysteine-rich C-terminal region. Alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Mar 2014],
细胞定位
Nucleus, PML body .
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