Choactase Polyclonal Antibody

产品详情

产品名称

Choactase Polyclonal Antibody

产品货号

YM-A17545

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,ELISA

分子量

82,70kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human Choactase. AA range:334-383

特异性

Choactase Polyclonal Antibody detects endogenous levels of Choactase protein.

基因名称

CHAT

蛋白名称

Choline O-acetyltransferase

别名

CHAT;Choline O-acetyltransferase;CHOACTase;ChAT;Choline acetylase

基因ID-1

1103

SwissProt

P28329

背景

This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform. [provided by RefSeq, May 2010],

细胞定位

nucleus,cytoplasm,cytosol,presynapse,