COL4A6 Polyclonal Antibody

产品详情

产品名称

COL4A6 Polyclonal Antibody

产品货号

YM-A17655

规格

50μL;100μL

种属反应

Human

实验应用

WB,IHC,IF,ELISA

分子量

160kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:40000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human Collagen IV alpha6. AA range:1201-1250

特异性

COL4A6 Polyclonal Antibody detects endogenous levels of COL4A6 protein.

基因名称

COL4A6

蛋白名称

Collagen alpha-6(IV) chain

别名

COL4A6;Collagen alpha-6;IV;chain

基因ID-1

1288

SwissProt

Q14031

背景

This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene, alpha 5 type IV collagen, so that the gene pair shares a common promoter. Deletions in the alpha 5 gene that extend into the alpha 6 gene result in diffuse leiomyomatosis accompanying the X-linked Alport syndrome caused by the deletion in the alpha 5 gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013],

细胞定位

Secreted, extracellular space, extracellular matrix, basement membrane.