CRSP150 Polyclonal Antibody

产品详情

产品名称

CRSP150 Polyclonal Antibody

产品货号

YM-A17734

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

IHC,IF,ELISA

分子量

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:40000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human MED14. AA range:701-750

特异性

CRSP150 Polyclonal Antibody detects endogenous levels of CRSP150 protein.

基因名称

MED14

蛋白名称

Mediator of RNA polymerase II transcription subunit 14

别名

MED14;ARC150;CRSP2;CXorf4;DRIP150;EXLM1;RGR1;TRAP170;Mediator of RNA polymerase II transcription subunit 14;Activator-recruited cofactor 150 kDa component;ARC150;Cofactor required for Sp1 transcriptional activation subunit 2;CRS

基因ID-1

9282

SwissProt

O60244

背景

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation. [provided by RefSeq, Jul 2008],

细胞定位

Nucleus .