CRSP34 Polyclonal Antibody

产品详情

产品名称

CRSP34 Polyclonal Antibody

产品货号

YM-A17735

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,ELISA

分子量

35kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from CRSP34 . at AA range: 90-170

特异性

CRSP34 Polyclonal Antibody detects endogenous levels of CRSP34 protein.

基因名称

MED27

蛋白名称

Mediator of RNA polymerase II transcription subunit 27

别名

MED27;CRSP34;CRSP8;Mediator of RNA polymerase II transcription subunit 27;Cofactor required for Sp1 transcriptional activation subunit 8;CRSP complex subunit 8;Mediator complex subunit 27;P37 TRAP/SMCC/PC2 subunit;Transcriptional co

基因ID-1

9442

SwissProt

Q6P2C8

背景

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2011],

细胞定位

Nucleus .