CYP11A1 Polyclonal Antibody

产品详情

产品名称

CYP11A1 Polyclonal Antibody

产品货号

YM-A17789

规格

50μL;100μL

种属反应

Human

实验应用

WB,ELISA

分子量

60kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;ELISA 1:5000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human Cytochrome P450 11A1. AA range:412-461

特异性

CYP11A1 Polyclonal Antibody detects endogenous levels of CYP11A1 protein.

基因名称

CYP11A1

蛋白名称

Cholesterol side-chain cleavage enzyme mitochondrial

别名

CYP11A1;CYP11A;Cholesterol side-chain cleavage enzyme;mitochondrial;CYPXIA1;Cholesterol desmolase;Cytochrome P450 11A1;Cytochrome P450;scc;

基因ID-1

1583

SwissProt

P05108

背景

cytochrome P450 family 11 subfamily A member 1(CYP11A1) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide. [provided by RefSeq, Jul 2008],

细胞定位

Mitochondrion inner membrane ; Peripheral membrane protein . Localizes to the matrix side of the mitochondrion inner membrane. .