CYP11B1/2 Polyclonal Antibody

产品详情

产品名称

CYP11B1/2 Polyclonal Antibody

产品货号

YM-A17790

规格

50μL;100μL

种属反应

Human

实验应用

WB,ELISA

分子量

57kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from the C-terminal region of human CYP11B1/2.

特异性

CYP11B1/2 Polyclonal Antibody detects endogenous levels of CYP11B1/2 protein.

基因名称

CYP11B1/CYP11B2

蛋白名称

Cytochrome P450 11B1 mitochondrial/Cytochrome P450 11B2 mitochondrial

别名

CYP11B1;S11BH;Cytochrome P450 11B1;mitochondrial;CYPXIB1;Cytochrome P-450c11;Cytochrome P450C11;Steroid 11-beta-hydroxylase;CYP11B2;Cytochrome P450 11B2, mitochondrial;Aldosterone synthase;ALDOS;Aldosterone-synthesizing enzyme;

基因ID-1

1584;1585

SwissProt

P15538;P19099

背景

cytochrome P450 family 11 subfamily B member 1(CYP11B1) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008],

细胞定位

Mitochondrion inner membrane ; Peripheral membrane protein .