CYP24A1 Polyclonal Antibody

产品详情

产品名称

CYP24A1 Polyclonal Antibody

产品货号

YM-A17800

规格

50μL;100μL

种属反应

Human,Rat,Mouse,

实验应用

WB,IHC,IF,ELISA

分子量

38kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human Cytochrome P450 24A1. AA range:411-460

特异性

CYP24A1 Polyclonal Antibody detects endogenous levels of CYP24A1 protein.

基因名称

CYP24A1

蛋白名称

1,25-dihydroxyvitamin D(3) 24-hydroxylase mitochondrial

别名

CYP24A1;CYP24;1;25-dihydroxyvitamin D;3;24-hydroxylase, mitochondrial;24-OHase;Vitamin D;3;24-hydroxylase;Cytochrome P450 24A1;Cytochrome P450-CC24

基因ID-1

1591

SwissProt

Q07973

背景

cytochrome P450 family 24 subfamily A member 1(CYP24A1) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

细胞定位

Mitochondrion .