Cytokeratin 13 Polyclonal Antibody

产品详情

产品名称

Cytokeratin 13 Polyclonal Antibody

产品货号

YM-A17857

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,IHC,IF,ELISA

分子量

52kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human Cytokeratin 13. AA range:233-282

特异性

Cytokeratin 13 Polyclonal Antibody detects endogenous levels of Cytokeratin 13 protein.

基因名称

KRT13

蛋白名称

Keratin type I cytoskeletal 13

别名

KRT13;Keratin;type I cytoskeletal 13;Cytokeratin-13;CK-13;Keratin-13;K13

基因ID-1

3860

SwissProt

P13646

背景

The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus. The type I cytokeratins are clustered in a region of chromosome 17q21.2. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been described. [provided by RefSeq, Jul 2008],

细胞定位

nucleus,intermediate filament,keratin filament,intermediate filament cytoskeleton,extracellular exosome,