Dio-1 Polyclonal Antibody

产品详情

产品名称

Dio-1 Polyclonal Antibody

产品货号

YM-A17940

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,IHC,IF,ELISA

分子量

244kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human DIDO1. AA range:161-210

特异性

Dio-1 Polyclonal Antibody detects endogenous levels of Dio-1 protein.

基因名称

DIDO1

蛋白名称

Death-inducer obliterator 1

别名

DIDO1;C20orf158;DATF1;KIAA0333;Death-inducer obliterator 1;DIO-1;hDido1;Death-associated transcription factor 1;DATF-1

基因ID-1

11083

SwissProt

Q9BTC0

背景

Apoptosis, a major form of cell death, is an efficient mechanism for eliminating unwanted cells and is of central importance for development and homeostasis in metazoan animals. In mice, the death inducer-obliterator-1 gene is upregulated by apoptotic signals and encodes a cytoplasmic protein that translocates to the nucleus upon apoptotic signal activation. When overexpressed, the mouse protein induced apoptosis in cell lines growing in vitro. This gene is similar to the mouse gene and therefore is thought to be involved in apoptosis. Alternatively spliced transcripts have been found for this gene, encoding multiple isoforms. [provided by RefSeq, Jul 2008],

细胞定位

Cytoplasm . Nucleus . Cytoplasm, cytoskeleton, spindle . Translocates to the nucleus after pro-apoptotic stimuli (By similarity). Translocates to the mitotic spindle upon loss of interaction with H3K4me3 during early mitosis. .