DOCK 180 Polyclonal Antibody

产品详情

产品名称

DOCK 180 Polyclonal Antibody

产品货号

YM-A17975

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,ELISA

分子量

215kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human DOCK1. AA range:1661-1710

特异性

DOCK 180 Polyclonal Antibody detects endogenous levels of DOCK 180 protein.

基因名称

DOCK1

蛋白名称

Dedicator of cytokinesis protein 1

别名

DOCK1;Dedicator of cytokinesis protein 1;180 kDa protein downstream of CRK;DOCK180

基因ID-1

1793

SwissProt

Q14185

背景

This gene encodes a member of the dedicator of cytokinesis protein family. Dedicator of cytokinesis proteins act as guanine nucleotide exchange factors for small Rho family G proteins. The encoded protein regulates the small GTPase Rac, thereby influencing several biological processes, including phagocytosis and cell migration. Overexpression of this gene has also been associated with certain cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014],

细胞定位

Cytoplasm . Membrane . Recruited to membranes via its interaction with phosphatidylinositol 3,4,5-trisphosphate. .