Dynein IC1 Polyclonal Antibody

产品详情

产品名称

Dynein IC1 Polyclonal Antibody

产品货号

YM-A18009

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,ELISA

分子量

79kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human DNAI1. AA range:211-260

特异性

Dynein IC1 Polyclonal Antibody detects endogenous levels of Dynein IC1 protein.

基因名称

DNAI1

蛋白名称

Dynein intermediate chain 1 axonemal

别名

DNAI1;Dynein intermediate chain 1;axonemal;Axonemal dynein intermediate chain 1

基因ID-1

27019

SwissProt

Q9UI46

背景

This gene encodes a member of the dynein intermediate chain family. The encoded protein is part of the dynein complex in respiratory cilia. The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generating proteins responsible for the sliding movement in axonemes. The intermediate and light chains, thought to form the base of the dynein arm, help mediate attachment and may also participate in regulating dynein activity. Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia and Kartagener syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],

细胞定位

Dynein axonemal particle . Cytoplasm, cytoskeleton, cilium axoneme .