DZIP3 Polyclonal Antibody

产品详情

产品名称

DZIP3 Polyclonal Antibody

产品货号

YM-A18020

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,IHC,IF,ELISA

分子量

140kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human DZIP3. AA range:681-730

特异性

DZIP3 Polyclonal Antibody detects endogenous levels of DZIP3 protein.

基因名称

DZIP3

蛋白名称

E3 ubiquitin-protein ligase DZIP3

别名

DZIP3;KIAA0675;E3 ubiquitin-protein ligase DZIP3;DAZ-interacting protein 3;RNA-binding ubiquitin ligase of 138 kDa;hRUL138

基因ID-1

9666

SwissProt

Q86Y13

背景

function:E3 Ubiquitin ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Able to specifically bind RNA.,pathway:Protein modification; protein ubiquitination.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Contains 1 RING-type zinc finger.,subunit:Interacts with DAZ proteins.,tissue specificity:Widely expressed at low level. Highly expressed in skeletal muscle, kidney and heart. Expressed at low level in placenta, lung, brain, liver and pancreas.,

细胞定位

Cytoplasm .