EDG-8 Polyclonal Antibody

产品详情

产品名称

EDG-8 Polyclonal Antibody

产品货号

YM-A18045

规格

50μL;100μL

种属反应

Human,Rat,Mouse,

实验应用

IHC,IF,ELISA

分子量

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human EDG8. AA range:335-384

特异性

EDG-8 Polyclonal Antibody detects endogenous levels of EDG-8 protein.

基因名称

S1PR5

蛋白名称

Sphingosine 1-phosphate receptor 5

别名

S1PR5;EDG8;Sphingosine 1-phosphate receptor 5;S1P receptor 5;S1P5;Endothelial differentiation G-protein-coupled receptor 8;Sphingosine 1-phosphate receptor Edg-8;S1P receptor Edg-8

基因ID-1

53637

SwissProt

Q9H228

背景

The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1; MIM 601974) are S1P receptors; others (e.g., EDG2; MIM 602282) are LPA receptors.[supplied by OMIM, Mar 2008],

细胞定位

Cell membrane; Multi-pass membrane protein.