EF-G2 Polyclonal Antibody

产品详情

产品名称

EF-G2 Polyclonal Antibody

产品货号

YM-A18049

规格

50μL;100μL

种属反应

Human,Rat,Mouse,

实验应用

WB,IHC,IF,ELISA

分子量

87kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human GFM2. AA range:441-490

特异性

EF-G2 Polyclonal Antibody detects endogenous levels of EF-G2 protein.

基因名称

GFM2

蛋白名称

Ribosome-releasing factor 2 mitochondrial

别名

GFM2;EFG2;MSTP027;Ribosome-releasing factor 2;mitochondrial;RRF2mt;Elongation factor G 2, mitochondrial;EF-G2mt;mEF-G 2;Elongation factor G2;hEFG2

基因ID-1

84340

SwissProt

Q969S9

背景

Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. This gene encodes one of the mitochondrial translation elongation factors, which is a GTPase that plays a role at the termination of mitochondrial translation by mediating the disassembly of ribosomes from messenger RNA . Its role in the regulation of normal mitochondrial function and in disease states attributed to mitochondrial dysfunction is not known. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2013],

细胞定位

Mitochondrion .